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While short-term use of glutathione should not affect zinc levels, long-term use has been linked to zinc deficiency

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Am J Dig Dis 22:605610 Heard KJ, Green JL, James LP, Judge BS, Zolot L, Rhyee S, Dart RC (2011) Acetaminophen-cysteine adducts during therapeutic dosing and following overdose

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RIPK3 expression was significantly upregulated in the human normal colon epithelial cell line NCM460

High doses may lead to the K-hole phenomenon, characterized by extreme dissociation without loss of consciousness (Malhotra et al., 1996)